{"id":3529,"date":"2024-06-01T21:08:24","date_gmt":"2024-06-01T19:08:24","guid":{"rendered":"https:\/\/altrion-distribution.ch\/bibliographie-dispositifs-medicaux\/"},"modified":"2026-10-24T13:57:44","modified_gmt":"2026-10-24T11:57:44","slug":"bibliographie-dispositifs-medicaux","status":"publish","type":"page","link":"https:\/\/altrion-distribution.ch\/fr\/bibliographie-dispositifs-medicaux\/","title":{"rendered":"Bibliographie"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-145nae-5360f43ddb78f81ea8c00037249094a2\">\n.avia-section.av-145nae-5360f43ddb78f81ea8c00037249094a2{\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/altrion-distribution.ch\/wp-content\/uploads\/2024\/06\/laboratorio.webp);\nbackground-position:50% 50%;\nbackground-attachment:scroll;\n}\n.avia-section.av-145nae-5360f43ddb78f81ea8c00037249094a2 .av-section-color-overlay{\nopacity:0.6;\nbackground-color:#084a79;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-145nae-5360f43ddb78f81ea8c00037249094a2 main_color avia-section-default avia-no-border-styling  avia-builder-el-0  el_before_av_submenu  avia-builder-el-first  avia-full-stretch avia-bg-style-scroll av-section-color-overlay-active av-minimum-height av-minimum-height-custom av-height-custom  container_wrap fullsize'  data-section-bg-repeat='stretch' data-av_minimum_height_px='300'><div class=\"av-section-color-overlay-wrap\"><div class=\"av-section-color-overlay\"><\/div><div class='container av-section-cont-open' style='height:300px'><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-3529'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-jgf3pjem-5106eb5975420097a59e461c409b1c03\">\n#top .flex_column.av-jgf3pjem-5106eb5975420097a59e461c409b1c03{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-jgf3pjem-5106eb5975420097a59e461c409b1c03{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n.responsive #top #wrap_all .flex_column.av-jgf3pjem-5106eb5975420097a59e461c409b1c03{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n<\/style>\n<div  class='flex_column av-jgf3pjem-5106eb5975420097a59e461c409b1c03 av_one_full  avia-builder-el-1  avia-builder-el-no-sibling  first flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-jgs0mam9-da3f627ba29eaf47957199328a1b250d\">\n#top .av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d{\nmargin:0 0 0 0;\npadding-bottom:0;\ncolor:#ffffff;\nfont-size:4vw;\n}\nbody .av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d .av-special-heading-tag{\nfont-size:4vw;\n}\n.av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d .special-heading-inner-border{\nborder-color:#ffffff;\n}\n.av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d .av-subheading{\nfont-size:25px;\n}\n\n@media only screen and (min-width: 480px) and (max-width: 767px){ \n#top #wrap_all .av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n\n@media only screen and (max-width: 479px){ \n#top #wrap_all .av-special-heading.av-jgs0mam9-da3f627ba29eaf47957199328a1b250d .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n<\/style>\n<div  class='av-special-heading av-jgs0mam9-da3f627ba29eaf47957199328a1b250d av-special-heading-h1 custom-color-heading blockquote modern-quote modern-centered  avia-builder-el-2  avia-builder-el-no-sibling  av-inherit-size'><h1 class='av-special-heading-tag '  itemprop=\"headline\"  >Bibliographie scientifique et documentation clinique<\/h1><div class='av_custom_color av-subheading av-subheading_below'><p>Preuves scientifiques et r\u00e9f\u00e9rences bibliographiques sur les technologies Seffiline et M.A.S. Medical.<\/p>\n<\/div><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><\/div><\/div><\/div><\/main><!-- close content main element --><\/div><\/div><\/div><div class='clear'><\/div><div id='sub_menu1'  class='av-submenu-container av-mvdtfsf2-3f394dfc054cbca4e236bf6c02c28880 alternate_color  avia-builder-el-3  el_after_av_section  el_before_av_section  av-sticky-submenu submenu-not-first container_wrap fullsize' style='z-index:301' ><div class='container av-menu-mobile-disabled av-submenu-pos-center'><ul id='av-custom-submenu-1' class='av-subnav-menu' role='menu'>\n<li class='menu-item av-mvdtfgoc-4f2e4beaaaf8a64e46254b1c40e5a1f4 menu-item-top-level menu-item-top-level-1' role='menuitem'><a href='#mas-medical'  ><span class='avia-bullet'><\/span><span class='avia-menu-text'>M.A.S. Medical<\/span><\/a><\/li>\n<li class='menu-item av-mvdtfpqx-bd2c7473634b746ed0abb9d57781d0e4 menu-item-top-level menu-item-top-level-2' role='menuitem'><a href='#seffiline'  ><span class='avia-bullet'><\/span><span class='avia-menu-text'>Seffiline<\/span><\/a><\/li>\n<\/ul><\/div><\/div><div class='sticky_placeholder'><\/div><\/p>\n<div id='mas-medical'  class='avia-section av-qet8u-bfb1ad49cbe69d84f9fa5dd56538cfb1 main_color avia-section-default avia-no-border-styling  avia-builder-el-4  el_after_av_submenu  el_before_av_section  avia-bg-style-scroll av-minimum-height av-minimum-height-50 av-height-50  container_wrap fullsize'   data-av_minimum_height_pc='50' data-av_min_height_opt='50'><div class='container av-section-cont-open' ><div class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-3529'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mvdto9cv-bce64da5064c32ac10089e7fd1797eac\">\n#top .av-special-heading.av-mvdto9cv-bce64da5064c32ac10089e7fd1797eac{\nmargin:0 0 0 0;\npadding-bottom:0;\n}\nbody .av-special-heading.av-mvdto9cv-bce64da5064c32ac10089e7fd1797eac .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-mvdto9cv-bce64da5064c32ac10089e7fd1797eac .av-special-heading-tag{\nfont-size:30px;\n}\n.av-special-heading.av-mvdto9cv-bce64da5064c32ac10089e7fd1797eac .av-subheading{\nfont-size:25px;\n}\n<\/style>\n<div  class='av-special-heading av-mvdto9cv-bce64da5064c32ac10089e7fd1797eac av-special-heading-h2 custom-color-heading  avia-builder-el-5  el_before_av_hr  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >Bibliographie M.A.S. Medical<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-c2byno-78de856c6aa3404e7807eead7fae107b\">\n#top .hr.hr-invisible.av-c2byno-78de856c6aa3404e7807eead7fae107b{\nheight:20px;\n}\n<\/style>\n<div  class='hr av-c2byno-78de856c6aa3404e7807eead7fae107b hr-invisible  avia-builder-el-6  el_after_av_heading  el_before_av_one_full '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div class='flex_column_table av-b29iq-cba8d9e61a0d9625f8d091c7d6fa024d sc-av_one_full av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-b29iq-cba8d9e61a0d9625f8d091c7d6fa024d\">\n#top .flex_column_table.av-equal-height-column-flextable.av-b29iq-cba8d9e61a0d9625f8d091c7d6fa024d{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-b29iq-cba8d9e61a0d9625f8d091c7d6fa024d{\nborder-radius:3px 3px 3px 3px;\npadding:20px 40px 20px 40px;\nbackground-color:#f1f1f2;\n}\n<\/style>\n<div  class='flex_column av-b29iq-cba8d9e61a0d9625f8d091c7d6fa024d av_one_full  avia-builder-el-7  el_after_av_hr  el_before_av_hr  first flex_column_table_cell av-equal-height-column av-align-middle  '     ><section  class='av_textblock_section av-jgds8wgh-3-beeceb959ce10ad85c2ec2dc45bf693e '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><section class=\"av_textblock_section av-k1hx341g-690671d8cf0d4e5f47b1a385f1153a78 \">\n<div class=\"avia_textblock\">\n<p><strong>Note d\u2019interpr\u00e9tation. <\/strong>La litt\u00e9rature cit\u00e9e \u00e9taye le principe g\u00e9n\u00e9ral du recours \u00e0 des syst\u00e8mes clos pour la collecte et la gestion des fluides chirurgicaux, par rapport aux syst\u00e8mes ouverts traditionnels ou \u00e0 bocaux d\u2019aspiration. Les r\u00e9sultats des diff\u00e9rentes \u00e9tudes ne doivent pas \u00eatre pr\u00e9sent\u00e9s comme des performances directement d\u00e9montr\u00e9es pour le DSX, sauf si des donn\u00e9es sp\u00e9cifiques au dispositif sont disponibles. <\/p>\n<\/div>\n<\/section>\n<\/div><\/section><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-bfdhkk-11536011da3130f69dc8a9f32a24002a\">\n#top .hr.hr-invisible.av-bfdhkk-11536011da3130f69dc8a9f32a24002a{\nheight:20px;\n}\n<\/style>\n<div  class='hr av-bfdhkk-11536011da3130f69dc8a9f32a24002a hr-invisible  avia-builder-el-9  el_after_av_one_full  el_before_av_three_fourth '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-9wkhy-d97d40b161b39be6cbde26330a6f78fa\">\n#top .flex_column.av-9wkhy-d97d40b161b39be6cbde26330a6f78fa{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-9wkhy-d97d40b161b39be6cbde26330a6f78fa{\nborder-radius:3px 3px 3px 3px;\npadding:0px 0px 0px 0px;\n}\n.responsive #top #wrap_all .flex_column.av-9wkhy-d97d40b161b39be6cbde26330a6f78fa{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n<\/style>\n<div  class='flex_column av-9wkhy-d97d40b161b39be6cbde26330a6f78fa av_three_fourth  avia-builder-el-10  el_after_av_hr  el_before_av_hr  first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-jgds8wgh-224bcd5d0dccf4e29abbb2c22f0e7019 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>R\u00e9duction de l\u2019exposition professionnelle aux liquides biologiques<\/strong><\/p>\n<p>Une \u00e9tude comparative men\u00e9e au bloc op\u00e9ratoire lors d\u2019interventions arthroscopiques, urologiques et orthop\u00e9diques a compar\u00e9 un syst\u00e8me clos de gestion des fluides \u00e0 un syst\u00e8me ouvert traditionnel \u00e0 bocaux d\u2019aspiration. Le syst\u00e8me clos a r\u00e9duit le nombre de situations d\u2019exposition potentielle du personnel \u00e0 des fluides dangereux pour certains types d\u2019interventions. En outre, le syst\u00e8me ouvert a exig\u00e9 pr\u00e8s de 3,5 fois plus de temps de travail du personnel pour l\u2019installation, la gestion perop\u00e9ratoire et l\u2019\u00e9limination apr\u00e8s l\u2019intervention.  <\/p>\n<p><strong>Moins de manipulation des fluides et une meilleure ergonomie<\/strong><\/p>\n<p>L\u2019\u00e9tude europ\u00e9enne GREEN a compar\u00e9 un syst\u00e8me automatis\u00e9 clos de gestion des fluides aux bocaux d\u2019aspiration traditionnels lors d\u2019interventions urologiques et orthop\u00e9diques. Le syst\u00e8me clos a r\u00e9duit de 98,5 % le poids des d\u00e9chets trait\u00e9s li\u00e9s au dispositif et de 96 % le poids des fluides chirurgicaux que le personnel devait d\u00e9placer physiquement, soit en moyenne environ 34 kg de moins par intervention. <\/p>\n<p><strong>Moins de d\u00e9versements et d\u2019incidents op\u00e9rationnels<\/strong><\/p>\n<p>Un audit publi\u00e9 en 2024 portant sur 224 interventions urologiques a d\u00e9crit les difficult\u00e9s li\u00e9es \u00e0 la gestion traditionnelle des liquides d\u2019irrigation au moyen de seaux et de bocaux : risques de d\u00e9versement, exposition du personnel \u00e0 du mat\u00e9riel biologique, interruptions op\u00e9ratoires et consommation importante de mat\u00e9riel \u00e0 usage unique. Les auteurs examinent l\u2019introduction de syst\u00e8mes automatis\u00e9s clos comme strat\u00e9gie possible pour am\u00e9liorer la s\u00e9curit\u00e9 et l\u2019efficacit\u00e9. <\/p>\n<p><strong>Contamination environnementale li\u00e9e aux syst\u00e8mes de collecte traditionnels<\/strong><\/p>\n<p>Une \u00e9tude microbiologique portant sur les bocaux d\u2019aspiration utilis\u00e9s au bloc op\u00e9ratoire a mis en \u00e9vidence une contamination du raccord au r\u00e9seau de vide dans 26,1 % des cas et une contamination de l\u2019environnement de la zone de vidange et de nettoyage dans 59,2 % des cas. Dans 28,6 % des cas, le micro-organisme identifi\u00e9 dans l\u2019environnement \u00e9tait identique \u00e0 celui pr\u00e9sent dans le bocal. <\/p>\n<p><strong>Autres donn\u00e9es sur le principe du drainage clos<\/strong><\/p>\n<p>D\u2019autres \u00e9tudes sur les syst\u00e8mes de drainage chirurgical ont montr\u00e9 une diminution des situations d\u2019exposition et de contamination lorsque l\u2019ouverture, la vidange et la manipulation des r\u00e9cipients sont limit\u00e9es. Dans une \u00e9tude randomis\u00e9e, la probabilit\u00e9 d\u2019exposition aux fluides avec le syst\u00e8me conventionnel \u00e9tait environ cinq fois plus \u00e9lev\u00e9e qu\u2019avec le syst\u00e8me clos \u00e9valu\u00e9. Dans une autre simulation men\u00e9e aupr\u00e8s de 58 infirmi\u00e8res et infirmiers, la manipulation des syst\u00e8mes traditionnels a entra\u00een\u00e9 une contamination de l\u2019op\u00e9rateur ou de l\u2019environnement dans 40 \u00e0 45 % des proc\u00e9dures simul\u00e9es, alors qu\u2019aucun \u00e9pisode de contamination n\u2019a \u00e9t\u00e9 observ\u00e9 avec le syst\u00e8me clos \u00e9valu\u00e9.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8ix778-ed7da31efd155ecea1a63741dbf5ec6a\">\n#top .hr.hr-invisible.av-8ix778-ed7da31efd155ecea1a63741dbf5ec6a{\nheight:20px;\n}\n<\/style>\n<div  class='hr av-8ix778-ed7da31efd155ecea1a63741dbf5ec6a hr-invisible  avia-builder-el-12  el_after_av_three_fourth  el_before_av_one_full '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div class='flex_column_table av-2nv190-c8d87fc2055cafaad49571daf40b9a49 sc-av_one_full av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2nv190-c8d87fc2055cafaad49571daf40b9a49\">\n#top .flex_column_table.av-equal-height-column-flextable.av-2nv190-c8d87fc2055cafaad49571daf40b9a49{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-2nv190-c8d87fc2055cafaad49571daf40b9a49{\nborder-radius:3px 3px 3px 3px;\npadding:20px 40px 20px 40px;\nbackground-color:#f1f1f2;\n}\n<\/style>\n<div  class='flex_column av-2nv190-c8d87fc2055cafaad49571daf40b9a49 av_one_full  avia-builder-el-13  el_after_av_hr  el_before_av_hr  first flex_column_table_cell av-equal-height-column av-align-middle  '     ><section  class='av_textblock_section av-mun6acgd-143501a585089e00bf5253242e0e1adb '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><section class=\"av_textblock_section av-k1hx341g-690671d8cf0d4e5f47b1a385f1153a78 \">\n<div class=\"avia_textblock\">\n<p><strong>En r\u00e9sum\u00e9<\/strong><\/p>\n<ul>\n<li>r\u00e9duire les situations d\u2019exposition des op\u00e9rateurs au sang et aux liquides biologiques ;<\/li>\n<li>limiter les d\u00e9versements et la contamination de l\u2019environnement ;<\/li>\n<li>r\u00e9duire la manutention manuelle de r\u00e9cipients lourds ;<\/li>\n<li>diminuer le temps consacr\u00e9 au remplacement et \u00e0 l\u2019\u00e9limination des bocaux ;<\/li>\n<li>am\u00e9liorer l\u2019efficacit\u00e9 op\u00e9rationnelle au bloc op\u00e9ratoire ;<\/li>\n<li>r\u00e9duire, dans certaines configurations, la quantit\u00e9 de d\u00e9chets li\u00e9s \u00e0 la gestion des fluides.<\/li>\n<\/ul>\n<\/div>\n<\/section>\n<\/div><\/section><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-33h8g4-ceb4e3294fa563ab3c3734f4bdffc5d1\">\n#top .hr.hr-invisible.av-33h8g4-ceb4e3294fa563ab3c3734f4bdffc5d1{\nheight:50px;\n}\n<\/style>\n<div  class='hr av-33h8g4-ceb4e3294fa563ab3c3734f4bdffc5d1 hr-invisible  avia-builder-el-15  el_after_av_one_full  el_before_av_three_fourth '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-42b3c4-d9a362bccebb03e0de6318224b099c59\">\n#top .flex_column.av-42b3c4-d9a362bccebb03e0de6318224b099c59{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-42b3c4-d9a362bccebb03e0de6318224b099c59{\nborder-radius:3px 3px 3px 3px;\npadding:0px 0px 0px 0px;\n}\n.responsive #top #wrap_all .flex_column.av-42b3c4-d9a362bccebb03e0de6318224b099c59{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n<\/style>\n<div  class='flex_column av-42b3c4-d9a362bccebb03e0de6318224b099c59 av_three_fourth  avia-builder-el-16  el_after_av_hr  avia-builder-el-last  first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-mun6e5m1-e3cdbd6bdf03a2300ec46f6c1e75136c '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>Bibliographie et liens vers les sources<\/strong><\/p>\n<ol>\n<li> <strong>Horn M, Patel N, MacLellan DM, Millard N.<\/strong> Traditional canister-based open waste management system versus closed system: hazardous exposure prevention and operating theatre staff satisfaction. ORNAC J. 2016;34(2):36-50. PMID: 27509767. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27509767\/\">Voir sur PubMed<\/a><\/li>\n<li> <strong>GREEN Study.<\/strong> Neptune versus canister-based surgical waste management in Europe: results of the GREEN study. 2023. PMID: 37663714. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37663714\/\">Voir sur PubMed<\/a><\/li>\n<li> <strong>An Audit on the Safety and Efficiency of Irrigation Fluid Disposal in Urology: Time to Implement Closed Waste Management Systems?<\/strong> Cureus. 2024. PMID: 39559434. PMCID: PMC11573424. DOI: 10.7759\/cureus.73939. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39559434\/\">Voir sur PubMed<\/a><\/li>\n<li> <strong>Vassal S, Mager G, Massot J, Maisonnet M.<\/strong> Microbiological aspects of nosocomial risks of suction bottles. Ann Chir. 1989;43(6):465-468. PMID: 2817747. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2817747\/\">Voir sur PubMed<\/a><\/li>\n<li> <strong>Zerbe MB, McArdle A, Goldrick B, Francis M.<\/strong> Reported blood exposure rates and staff nurse satisfaction with a closed surgical drainage system. Am J Infect Control. 1996;24(3):190-198. DOI: 10.1016\/S0196-6553(96)90012-7. PMID: 8806996. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8806996\/\">Voir sur PubMed<\/a><\/li>\n<li> <strong>Exposure risks related to the management of three wound drainage systems.<\/strong> 1996. PMID: 8902108. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8902108\/\">Voir sur PubMed<\/a><\/li>\n<li> <strong>Droog L, van der Sijp J, Hoppe T, et al.<\/strong> A life cycle assessment of disposing intra-operative collected fluids, a comparative study between the Neptune 3 versus canister drainage. Sci Rep. 2025;15:36587. PMID: 41120492. DOI: 10.1038\/s41598-025-20375-1. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41120492\/\">Voir sur PubMed<\/a><\/li>\n<\/ol>\n<p><strong>Source bibliographique :<\/strong> PubMed \/ U.S. National Library of Medicine (NLM).<\/p>\n<\/div><\/section><\/div>\n\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='seffiline'  class='avia-section av-mvdue352-f3e5cefca11478ea0dc7583ccfe28a9e main_color avia-section-default avia-no-border-styling  avia-builder-el-18  el_after_av_section  el_before_av_section  avia-bg-style-scroll av-minimum-height av-minimum-height-50 av-height-50  container_wrap fullsize'   data-av_minimum_height_pc='50' data-av_min_height_opt='50'><div class='container av-section-cont-open' ><div class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-3529'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mvductje-6d6ba6258ae1ead70e96c36c23199d6d\">\n#top .av-special-heading.av-mvductje-6d6ba6258ae1ead70e96c36c23199d6d{\nmargin:0 0 0 0;\npadding-bottom:0;\n}\nbody .av-special-heading.av-mvductje-6d6ba6258ae1ead70e96c36c23199d6d .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-mvductje-6d6ba6258ae1ead70e96c36c23199d6d .av-special-heading-tag{\nfont-size:30px;\n}\n.av-special-heading.av-mvductje-6d6ba6258ae1ead70e96c36c23199d6d .av-subheading{\nfont-size:25px;\n}\n<\/style>\n<div  class='av-special-heading av-mvductje-6d6ba6258ae1ead70e96c36c23199d6d av-special-heading-h2 custom-color-heading  avia-builder-el-19  el_before_av_hr  avia-builder-el-first '><h2 class='av-special-heading-tag '  itemprop=\"headline\"  >Bibliographie Seffiline<\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mvduhvaf-1c8519e82c35b3b2adf796e9da25bc56\">\n#top .hr.hr-invisible.av-mvduhvaf-1c8519e82c35b3b2adf796e9da25bc56{\nheight:10px;\n}\n<\/style>\n<div  class='hr av-mvduhvaf-1c8519e82c35b3b2adf796e9da25bc56 hr-invisible  avia-builder-el-20  el_after_av_heading  el_before_av_textblock '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<section  class='av_textblock_section av-mvdughce-b013d1899852ea776358aa3029d547b5 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><section class=\"av_textblock_section av-k1hx341g-690671d8cf0d4e5f47b1a385f1153a78 \">\n<div class=\"avia_textblock\">\n<h3><strong>Fondements scientifiques et applications du tissu adipeux autologue<\/strong><\/h3>\n<\/div>\n<\/section>\n<\/div><\/section>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-spc7o-cbb0c051799ca7cc0a7a660fbe56397c\">\n#top .hr.hr-invisible.av-spc7o-cbb0c051799ca7cc0a7a660fbe56397c{\nheight:20px;\n}\n<\/style>\n<div  class='hr av-spc7o-cbb0c051799ca7cc0a7a660fbe56397c hr-invisible  avia-builder-el-22  el_after_av_textblock  el_before_av_three_fourth '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5amtbo-77851e6f0bd09719c4c93f5fe2919f65\">\n#top .flex_column.av-5amtbo-77851e6f0bd09719c4c93f5fe2919f65{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-5amtbo-77851e6f0bd09719c4c93f5fe2919f65{\nborder-radius:3px 3px 3px 3px;\npadding:0px 0px 0px 0px;\n}\n.responsive #top #wrap_all .flex_column.av-5amtbo-77851e6f0bd09719c4c93f5fe2919f65{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n<\/style>\n<div  id=\"mas-medical\"  class='flex_column av-5amtbo-77851e6f0bd09719c4c93f5fe2919f65 av_three_fourth  avia-builder-el-23  el_after_av_hr  el_before_av_hr  first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-mvduj5lk-5fb07246d08980fd33565cfdb63cafdb '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><ol>\n<li><strong> Le tissu adipeux, une ressource biologique<\/strong><\/li>\n<\/ol>\n<p>Le tissu adipeux est un tissu conjonctif sp\u00e9cialis\u00e9 qui, outre sa fonction de r\u00e9serve \u00e9nerg\u00e9tique, exerce d\u2019importantes activit\u00e9s endocrines et m\u00e9taboliques et participe \u00e0 la r\u00e9gulation de l\u2019hom\u00e9ostasie tissulaire.<\/p>\n<p>Il se compose d\u2019adipocytes matures, de matrice extracellulaire, de cellules endoth\u00e9liales, de p\u00e9ricytes, de cellules immunitaires ainsi que de populations cellulaires stromales et prog\u00e9nitrices, regroup\u00e9es dans la fraction stromale vasculaire, ou <em>Stromal Vascular Fraction<\/em> (SVF).<\/p>\n<p>Parmi ces populations, les cellules stromales d\u2019origine adipeuse (<em>Adipose-Derived Stromal\/Stem Cells<\/em>, ADSCs) pr\u00e9sentent un int\u00e9r\u00eat particulier : elles sont largement \u00e9tudi\u00e9es en m\u00e9decine r\u00e9g\u00e9n\u00e9rative pour leurs propri\u00e9t\u00e9s biologiques.<\/p>\n<p>Les ADSCs se caract\u00e9risent par :<\/p>\n<ul>\n<li>Une capacit\u00e9 de prolif\u00e9ration et de diff\u00e9renciation dans des conditions exp\u00e9rimentales sp\u00e9cifiques.<\/li>\n<li>Une activit\u00e9 paracrine via la lib\u00e9ration de facteurs de croissance, de cytokines et de m\u00e9diateurs biologiques.<\/li>\n<li>Une implication potentielle dans les processus d\u2019angiogen\u00e8se et de remodelage de la matrice extracellulaire.<\/li>\n<li>Une possible modulation de la r\u00e9ponse inflammatoire et des processus de r\u00e9paration tissulaire.<\/li>\n<\/ul>\n<p>Ces caract\u00e9ristiques ont favoris\u00e9 le d\u00e9veloppement de techniques de pr\u00e9l\u00e8vement et de pr\u00e9paration du tissu adipeux visant \u00e0 en pr\u00e9server, autant que possible, les composants structurels et cellulaires.<\/p>\n<p>Il est important de distinguer le tissu adipeux utilis\u00e9 comme greffon autologue des populations cellulaires isol\u00e9es ou expandues en laboratoire : il s\u2019agit de pr\u00e9parations diff\u00e9rentes sur le plan biologique comme sur le plan r\u00e9glementaire.<\/p>\n<ol start=\"2\">\n<li><strong> La technique SEFFI : Superficial Enhanced Fluid Fat Injection<\/strong><\/li>\n<\/ol>\n<p>La technologie SEFFILINE repose sur les principes de la technique <em>Superficial Enhanced Fluid Fat Injection<\/em> (SEFFI), d\u00e9crite dans la litt\u00e9rature scientifique comme une m\u00e9thode de pr\u00e9l\u00e8vement et d\u2019utilisation du tissu adipeux autologue superficiel.<\/p>\n<p>La technique consiste \u00e0 pr\u00e9lever le tissu adipeux \u00e0 l\u2019aide de dispositifs d\u00e9di\u00e9s, puis \u00e0 pr\u00e9parer le mat\u00e9riel en vue de la greffe.<\/p>\n<p>L\u2019une de ses particularit\u00e9s est l\u2019attention port\u00e9e au plan anatomique de pr\u00e9l\u00e8vement. Le tissu adipeux superficiel pr\u00e9sente des caract\u00e9ristiques structurelles et cellulaires qui ont fait l\u2019objet d\u2019\u00e9tudes sp\u00e9cifiques, notamment en ce qui concerne la composante stromale. <\/p>\n<p>Les techniques SEFFI et Micro-SEFFI ont \u00e9t\u00e9 \u00e9tudi\u00e9es afin d\u2019\u00e9valuer les caract\u00e9ristiques du tissu obtenu, la pr\u00e9sence de cellules viables et la possibilit\u00e9 d\u2019utiliser ce mat\u00e9riel dans des proc\u00e9dures de greffe autologue.<\/p>\n<p>Les \u00e9tudes de caract\u00e9risation ont identifi\u00e9 des populations stromales adipeuses dans le mat\u00e9riel pr\u00e9lev\u00e9 et mis en \u00e9vidence certaines de leurs propri\u00e9t\u00e9s biologiques en conditions exp\u00e9rimentales.<\/p>\n<p>Toutefois, la pr\u00e9sence de cellules stromales viables ne constitue pas, en soi, une preuve d\u2019efficacit\u00e9 r\u00e9g\u00e9n\u00e9rative clinique.<\/p>\n<ol start=\"3\">\n<li><strong> M\u00e9canismes biologiques d\u2019int\u00e9r\u00eat<\/strong><\/li>\n<\/ol>\n<p><strong>3.1 Activit\u00e9 paracrine<\/strong><\/p>\n<p>Les cellules stromales adipeuses peuvent produire des m\u00e9diateurs biologiques impliqu\u00e9s dans la communication intercellulaire, notamment des facteurs associ\u00e9s \u00e0 la r\u00e9gulation de l\u2019angiogen\u00e8se, de la r\u00e9ponse inflammatoire et du remodelage tissulaire.<\/p>\n<p>Parmi les facteurs \u00e9tudi\u00e9s figurent le VEGF (<em>Vascular Endothelial Growth Factor<\/em>), l\u2019HGF (<em>Hepatocyte Growth Factor<\/em>) et d\u2019autres m\u00e9diateurs impliqu\u00e9s dans les processus de r\u00e9paration.<\/p>\n<p>Leur activit\u00e9 d\u00e9pend des conditions biologiques locales, des caract\u00e9ristiques du tissu et des modalit\u00e9s de pr\u00e9paration.<\/p>\n<p><strong>3.2 Angiogen\u00e8se et microcirculation<\/strong><\/p>\n<p>La composante stromale et vasculaire du tissu adipeux suscite l\u2019int\u00e9r\u00eat en raison de sa contribution possible aux processus de n\u00e9ovascularisation et au maintien du microenvironnement tissulaire.<\/p>\n<p>Les donn\u00e9es exp\u00e9rimentales sugg\u00e8rent un r\u00f4le potentiel de ces composants dans la r\u00e9gulation de la formation de nouveaux vaisseaux sanguins. Toutefois, l\u2019ampleur et la pertinence clinique de ces effets varient selon l\u2019application. <\/p>\n<p><strong>3.3 Matrice extracellulaire<\/strong><\/p>\n<p>Le tissu adipeux contient une matrice extracellulaire compos\u00e9e principalement de prot\u00e9ines structurelles et d\u2019\u00e9l\u00e9ments impliqu\u00e9s dans l\u2019organisation et le soutien m\u00e9canique des tissus.<\/p>\n<p>La pr\u00e9servation de la structure tissulaire lors du pr\u00e9l\u00e8vement et de la pr\u00e9paration peut influencer les caract\u00e9ristiques biologiques et m\u00e9caniques du greffon.<\/p>\n<p><strong>3.4 R\u00e9ponse inflammatoire et r\u00e9paration tissulaire<\/strong><\/p>\n<p>Les cellules stromales adipeuses ont \u00e9t\u00e9 \u00e9tudi\u00e9es pour leur capacit\u00e9 potentielle \u00e0 moduler certains processus inflammatoires.<\/p>\n<p>Ces m\u00e9canismes sont principalement document\u00e9s par des \u00e9tudes pr\u00e9cliniques et exp\u00e9rimentales. Leur traduction en b\u00e9n\u00e9fices cliniques n\u00e9cessite des \u00e9valuations sp\u00e9cifiques pour chaque indication th\u00e9rapeutique. <\/p>\n<ol start=\"4\">\n<li><strong> Donn\u00e9es scientifiques et applications cliniques<\/strong><\/li>\n<\/ol>\n<p><strong>4.1 M\u00e9decine esth\u00e9tique et rajeunissement du visage<\/strong><\/p>\n<p>La technique SEFFI a \u00e9t\u00e9 d\u00e9crite dans des publications consacr\u00e9es \u00e0 la correction des d\u00e9ficits volumiques et au traitement des modifications li\u00e9es au vieillissement du visage.<\/p>\n<p>Les \u00e9tudes rapportent des r\u00e9sultats concernant la restauration des volumes, la qualit\u00e9 de la peau et la satisfaction des patients.<\/p>\n<p>Une publication de 2015 a d\u00e9crit l\u2019application de la technique SEFFI au visage et \u00e0 la r\u00e9gion p\u00e9rioculaire, tandis que des \u00e9tudes ult\u00e9rieures ont approfondi la caract\u00e9risation biologique du tissu obtenu par Micro-SEFFI.<\/p>\n<p>Une \u00e9tude r\u00e9trospective de 2024, men\u00e9e aupr\u00e8s de 158 patients, a \u00e9valu\u00e9 un protocole combinant SEFFI et hydroxyapatite de calcium.<\/p>\n<p>Les r\u00e9sultats pr\u00e9sentent un int\u00e9r\u00eat clinique, mais le caract\u00e8re observationnel de l\u2019\u00e9tude et le recours \u00e0 des traitements combin\u00e9s ne permettent pas d\u2019attribuer l\u2019ensemble des effets observ\u00e9s \u00e0 la seule technique SEFFI.<\/p>\n<p><strong>4.2 Applications en trichologie<\/strong><\/p>\n<p>L\u2019int\u00e9r\u00eat pour le tissu adipeux autologue en trichologie d\u00e9coule principalement des recherches sur les interactions entre les cellules stromales adipeuses, le follicule pileux et le microenvironnement cutan\u00e9.<\/p>\n<p>Plusieurs \u00e9tudes exp\u00e9rimentales ont analys\u00e9 le r\u00f4le possible des facteurs s\u00e9cr\u00e9t\u00e9s par les ADSCs dans la r\u00e9gulation du cycle folliculaire et dans les processus biologiques li\u00e9s \u00e0 la croissance des cheveux.<\/p>\n<p>Les donn\u00e9es relatives aux m\u00e9canismes biologiques ne doivent toutefois pas \u00eatre consid\u00e9r\u00e9es comme \u00e9quivalentes \u00e0 une preuve d\u2019efficacit\u00e9 clinique d\u2019un dispositif ou d\u2019un protocole th\u00e9rapeutique donn\u00e9.<\/p>\n<p><strong>4.3 Applications musculo-squelettiques<\/strong><\/p>\n<p>L\u2019utilisation du tissu adipeux autologue a \u00e9galement \u00e9t\u00e9 \u00e9tudi\u00e9e dans le cadre des pathologies articulaires d\u00e9g\u00e9n\u00e9ratives, en particulier de l\u2019arthrose.<\/p>\n<p>Une \u00e9tude observationnelle portant sur 250 patients atteints d\u2019arthrose de la hanche ou du genou a analys\u00e9 les r\u00e9sultats cliniques associ\u00e9s \u00e0 l\u2019utilisation de tissu adipeux microfragment\u00e9 selon la technique SEFFICARE.<\/p>\n<p>Les r\u00e9sultats rapport\u00e9s sugg\u00e8rent une am\u00e9lioration possible de certains param\u00e8tres cliniques, mais doivent \u00eatre confirm\u00e9s par des \u00e9tudes prospectives contr\u00f4l\u00e9es, avec des groupes de comparaison et un suivi ad\u00e9quats.<\/p>\n<p><strong>4.4 Applications gyn\u00e9cologiques<\/strong><\/p>\n<p>L\u2019utilisation du tissu adipeux autologue a \u00e9galement fait l\u2019objet d\u2019\u00e9tudes pr\u00e9liminaires dans le domaine de la gyn\u00e9cologie r\u00e9g\u00e9n\u00e9rative.<\/p>\n<p>Une publication de 2021 a d\u00e9crit l\u2019application de la technique SEFFIGYN chez 12 patientes pr\u00e9sentant des sympt\u00f4mes du syndrome g\u00e9nito-urinaire de la m\u00e9nopause.<\/p>\n<p>L\u2019\u00e9tude a rapport\u00e9 des r\u00e9sultats pr\u00e9liminaires favorables sur certains param\u00e8tres cliniques et symptomatiques.<\/p>\n<p>La taille r\u00e9duite de l\u2019\u00e9chantillon et l\u2019absence de groupe t\u00e9moin ad\u00e9quat ne permettent toutefois pas de tirer des conclusions d\u00e9finitives sur l\u2019efficacit\u00e9 du traitement.<\/p>\n<ol start=\"5\">\n<li><strong> Limites des donn\u00e9es scientifiques<\/strong><\/li>\n<\/ol>\n<p>La litt\u00e9rature disponible sur les techniques SEFFI comprend des \u00e9tudes de caract\u00e9risation cellulaire, des recherches exp\u00e9rimentales, des \u00e9tudes observationnelles et des publications cliniques.<\/p>\n<p>Si ces \u00e9tudes apportent des informations sur le rationnel biologique et les applications possibles du tissu adipeux autologue, certaines limites m\u00e9thodologiques doivent \u00eatre prises en compte :<\/p>\n<ul>\n<li>Des effectifs parfois limit\u00e9s.<\/li>\n<li>La pr\u00e9sence d\u2019\u00e9tudes r\u00e9trospectives ou non contr\u00f4l\u00e9es.<\/li>\n<li>L\u2019h\u00e9t\u00e9rog\u00e9n\u00e9it\u00e9 des techniques de pr\u00e9paration et d\u2019administration.<\/li>\n<li>Differenze tra popolazioni di pazienti, indicazioni cliniche ed endpoint valutati.<\/li>\n<li>Une disponibilit\u00e9 limit\u00e9e de donn\u00e9es comparatives et de suivi \u00e0 long terme pour certaines applications.<\/li>\n<\/ul>\n<p>Les r\u00e9sultats obtenus avec une technique donn\u00e9e ou dans une indication sp\u00e9cifique ne peuvent pas \u00eatre automatiquement extrapol\u00e9s \u00e0 d\u2019autres dispositifs, protocoles ou situations cliniques.<\/p>\n<p>L\u2019\u00e9valuation du rapport b\u00e9n\u00e9fice-risque doit tenir compte des donn\u00e9es pertinentes pour la destination sp\u00e9cifique du dispositif.<\/p>\n<ol start=\"6\">\n<li><strong> Bibliographie scientifique<\/strong><\/li>\n<\/ol>\n<ol>\n<li>Bernardini F.P. et al. (2015). <em>Superficial Enhanced Fluid Fat Injection (SEFFI) to Correct Volume Defects and Skin Aging of the Face and Periocular Region.<\/em> Aesthetic Surgery Journal.<\/li>\n<li>Gennai A., Bernardini F.P. (2017). <em>Superficial Enhanced Fluid Fat Injection (SEFFI and MicroSEFFI) in Facial Rejuvenation.<\/em> CellR4, 5(1), e2239.<\/li>\n<li>Rossi M. et al. (2018). <em>Characterization of the Tissue and Stromal Cell Components of Micro-Superficial Enhanced Fluid Fat Injection (Micro-SEFFI) for Facial Aging Treatment.<\/em> Aesthetic Surgery Journal. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29905790\/\">PubMed<\/a>.<\/li>\n<li>Gennai A. et al. (2020). <em>SEFFI (Superficial Enhanced Fluid Fat Injection) for Aesthetic and Clinical Regenerative Treatments.<\/em> Global Journal of Dermatology &#038; Venereology, 8, 32\u201340.<\/li>\n<li><em>A New Approach to Regenerative Medicine in Gynecology<\/em> (2021). \u00c9tude observationnelle sur l\u2019utilisation de la technique SEFFIGYN. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34463351\/\">PubMed<\/a>. <\/li>\n<li><em>Guided SEFFI and CaHA: A Retrospective Observational Study of an Innovative Protocol for Regenerative Aesthetics<\/em> (2024). <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39124647\/\">PubMed<\/a>.<\/li>\n<li><em>Role of Autologous Micro-Fragmented Adipose Tissue in Osteoarthritis Treatment<\/em> (2024). \u00c9tude observationnelle portant sur 250 patients. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38929825\/\">PubMed<\/a>. <\/li>\n<\/ol>\n<p><strong>Autres r\u00e9f\u00e9rences scientifiques<\/strong><\/p>\n<p>Pour en savoir plus sur le rationnel biologique des cellules stromales d\u2019origine adipeuse :<\/p>\n<ol>\n<li>Zuk P.A. et al. (2002). <em>Human Adipose Tissue Is a Source of Multipotent Stem Cells.<\/em> Molecular Biology of the Cell, 13(12), 4279\u20134295.<\/li>\n<li>Gimble J.M., Katz A.J., Bunnell B.A. (2007). <em>Adipose-Derived Stem Cells for Regenerative Medicine.<\/em> Circulation Research, 100(9), 1249\u20131260.<\/li>\n<li>Kalluri R., LeBleu V.S. (2020). <em>The Biology, Function, and Biomedical Applications of Exosomes.<\/em> Science, 367(6478), eaau6977.<\/li>\n<\/ol>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4gdzsk-d5670e32e70e251279f1b4ca86673f11\">\n#top .hr.hr-invisible.av-4gdzsk-d5670e32e70e251279f1b4ca86673f11{\nheight:20px;\n}\n<\/style>\n<div  class='hr av-4gdzsk-d5670e32e70e251279f1b4ca86673f11 hr-invisible  avia-builder-el-25  el_after_av_three_fourth  el_before_av_one_full '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div class='flex_column_table av-39hxdg-0d0fc9f45829ff0f6c65500708f1db36 sc-av_one_full av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-39hxdg-0d0fc9f45829ff0f6c65500708f1db36\">\n#top .flex_column_table.av-equal-height-column-flextable.av-39hxdg-0d0fc9f45829ff0f6c65500708f1db36{\nmargin-top:0px;\nmargin-bottom:0px;\n}\n.flex_column.av-39hxdg-0d0fc9f45829ff0f6c65500708f1db36{\nborder-radius:3px 3px 3px 3px;\npadding:20px 40px 20px 40px;\nbackground-color:#f1f1f2;\n}\n<\/style>\n<div  class='flex_column av-39hxdg-0d0fc9f45829ff0f6c65500708f1db36 av_one_full  avia-builder-el-26  el_after_av_hr  avia-builder-el-last  first flex_column_table_cell av-equal-height-column av-align-middle  '     ><section  class='av_textblock_section av-mvdujpce-b6e63a98d0ee979acaca8478f1781469 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong>Note scientifique :<\/strong> les informations pr\u00e9sent\u00e9es d\u00e9crivent le rationnel biologique et les donn\u00e9es publi\u00e9es concernant les techniques d\u2019utilisation du tissu adipeux autologue. 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